From I-81:
- Exit onto I-581 (a left exit if coming from the north)
- Take 1st exit (right) onto Peters Creek Road (route 117 south)
- Turn right at end of ramp
- Follow Peters Creek to the end (4.7 miles) and turn right on Brandon Avenue
- Brandon Oaks will be on your left
From the east on Route 460:
- Route 460 West becomes Orange Avenue
- Right on Melrose Avenue ( 2.1 miles past the Roanoke Civic Center)
- Follow Melrose to Peters Creek Road (2.2 miles)
- Left on Peters Creek Road and follow to the end (2.4 miles)
- Right on Brandon Avenue
- Brandon Oaks will be on your left
From the south on Route 220:
- Just past the WalMart on the right and the Lowes on the left, bear right to Route 220 Business/Rt 419N/Franklin Rd exit
- At bottom of exit turn left on route 419 North (Electric Rd)
- Drive 6.3 miles (passing Tanglewood Mall) to Apperson Drive
- Right on Apperson Drive
- Drive 1.6 miles on Apperson, which will become Brandon Avenue
- Brandon Oaks will be on your right
From Route 221:
- Left on Route 419 north (Electric Road)
- Drive 3.8 miles on 419/Electric Rd to Apperson Drive
- Right on Apperson Drive
- Drive 1.6 miles on Apperson, which will become Brandon Avenue
- Brandon Oaks will be on your right